Supercritical Fluid Fractionation For Fractionation it is meant the separation of one or more components (from a mixture) with the employment of a miscible or immiscible solvent, thanks to a favorable repartition coefficient of the solute. The repartition … [Read more...] about Supercritical Fluid Fractionation
Atomization of CO2 Extracts
Atomization of CO2 Extracts Atomization occurs when a jet of liquid is broken down into more or less fine droplets. The ideal spray consists of drops of the same diameter. There are different technologies to obtain a micronized powder with CO2. The best known are: NEA (Near-critical Expansion … [Read more...] about Atomization of CO2 Extracts
SFC Supercritical Fluid Chromatography
SFC Supercritical Fluid Chromatography Chromatography is a fractionation technique widely utilized in the pharmaceutic industry, where productions are highly valuable, because it is a very efficient technique, and it allows to separate compounds which would be not … [Read more...] about SFC Supercritical Fluid Chromatography
Near-critical Expansion Atomization
Near-critical Expansion Atomization In NEA (Near-critical Expansion Atomization) process, the carbon dioxide is used in this process for the atomization and the crystallization of the product. The product subjected to the process is maintained in the liquid phase … [Read more...] about Near-critical Expansion Atomization
Rapid Expansion of Supercritical Solution
Rapid Expansion of Supercritical Solution RESS (Rapid Expansion of Supercritical Solution) is used generally to produce fine particles for the food, cosmetic and pharmaceutical industry.Organic material is dissolved in supercritical carbon dioxide and is used to … [Read more...] about Rapid Expansion of Supercritical Solution
Particles from Gas Saturated Solutions
Particles from Gas Saturated Solutions PGSS (Particles from Gas Saturated Solutions) is a technique for the production of microparticles of different materials of relatively low melting temperatures, such as polymers, waxes or fats. The process is based on the … [Read more...] about Particles from Gas Saturated Solutions
Supercritical AntiSolvent Micronization
Supercritical AntiSolvent Micronization As mentioned previously, the low solubility of a part of pharmaceutical products of interest limits the use of SC-CO2 as a solvent in the mico or nano production of particels. To solve this problem it was decided to use the SC-CO2 as anti-solvent … [Read more...] about Supercritical AntiSolvent Micronization
Supercritical Assisted Atomization
Supercritical Assisted Atomization SAA (Supercritical Assisted Atomization) process is focused on the nebulization of the liquid solution rather than using dense gas (SCF) to achieve precipitation by solubility reduction for the solute to be micro- or nano-sized. … [Read more...] about Supercritical Assisted Atomization
Terpenes extraction
Terpenes extraction Terpenes, main constituents of essential oils, commonly called “essences”, are widely spread both in the animal and plant kingdoms in the form of apparently different substances but all united by the same basic structure, all recognized as multiples of the compound 2 … [Read more...] about Terpenes extraction
The importance of Cleaning
The importance of Cleaning The cleaning procedure is an important practice: it has the same importance of the extraction process. Any extraction system needs to be cleaned periodically: this period depends on many factors, and All these topics have an impact on the cleaning period: … [Read more...] about The importance of Cleaning
Co-solvent pump
Co-solvent pump A liquid co-solvent can be added to CO2 to increase its solvent power on polar molecules.Indeed, supercritical CO2 is a good solvent for lipophilic (non-polar compounds like oils), whereas, it has a low affinity with hydrophilic (polar compounds like sugars).Process engineers … [Read more...] about Co-solvent pump
Quick closing system
Quick closing system Quick opening cover design needs only one-eighth of a turn rotation for sealing. Ideal for high pressure operations requiring repetitive opening/closing. The “Clover Leaf” Closure Reactors provide maximum ease for quick opening or closing of the cover. The cover is simply … [Read more...] about Quick closing system